The Shot Maker Society
XMD Wellness
Advanced Metabolic Support & GLP-1 Therapy
Guide
GUIDE 7: Advanced Metabolic Support & GLP-1 Therapy
What These Compounds Do, Why They’re Offered, and When They’re Helpful
GLP-1 medications are powerful tools for appetite regulation and metabolic support on their own. However, some clients benefit from additional metabolic and nutrient support during their journey — especially during periods of adjustment, fat loss, or increased demand on the body.
This guide explains:
What advanced metabolic support compounds are
Why they are sometimes included alongside GLP-1 therapy
What they support in the body
Why they are optional, not required
How to think about them without pressure or confusion
These supports are meant to enhance the experience, not replace or determine the success of GLP-1 therapy.
First: An Important Perspective
GLP-1 therapy works by:
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Regulating appetite signals
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Reducing food noise
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Improving insulin sensitivity
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Supporting metabolic balance
Advanced metabolic supports do not make GLP-1 “work.”
GLP-1 works on its own.
These compounds are offered to:
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Support energy levels
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Assist fat metabolism
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Help the body adapt during change
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Reduce fatigue for some clients
They are supportive tools, not requirements.
During weight loss and metabolic change, the body may experience:
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Lower calorie intake
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Increased nutrient demand
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Fatigue during adjustment
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Increased metabolic workload
Advanced metabolic supports may help some clients feel better during this process, particularly during:
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Early adjustment phases
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Higher-dose therapy
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Periods of rapid change
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Times of fatigue or low energy
Not everyone needs them — and not everyone will notice a difference.
Why Some Clients Choose Additional Support
Common Advanced Metabolic Support Compounds
Below are some of the compounds that may be offered if approved by a licensed medical provider and available.
Availability can vary.
What it supports:
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Cellular energy production
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Mitochondrial function
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Metabolic efficiency
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Recovery and fatigue support
Why it may be helpful:
Some clients experience improved energy and resilience, especially during periods of caloric reduction or metabolic adaptation.
Important note:
NAD+ is not a weight-loss drug — it supports how efficiently cells produce energy.
NAD+
(Nicotinamide Adenine Dinucleotide)
Vitamin B-12
What it supports:
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Energy metabolism
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Nervous system health
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Red blood cell production
Why it may be helpful:
Lower appetite and reduced intake can sometimes lead to lower B-vitamin intake. B-12 may support energy and overall wellbeing.
What it supports:
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Fat metabolism
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Transport of fatty acids into cells for energy
Why it may be helpful:
L-Carnitine supports the body’s ability to utilize stored fat for energy, particularly during weight loss phases.
L-Carnitine
Methionine, Inositol & Choline
These compounds support:
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Fat metabolism
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Liver function
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Metabolic pathways involved in energy utilization
They are often used together to support metabolic efficiency, not appetite suppression.
This is critical to understand You can:
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Lose weight
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Improve metabolic health
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Have successful GLP-1 outcomes
without using any advanced metabolic supports.
GLP-1 therapy does not depend on them.
These compounds are:
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Optional
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Supportive
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Based on individual needs
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Provider-guided
They are not a requirement and not a guarantee.
Why These Supports
Are Optional
Availability & Medical Approval
Advanced metabolic supports:
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Are only included if approved by a licensed provider
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May not always be available due to demand
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Are added based on medical appropriateness, not expectation
If they are not available, your GLP-1 therapy remains complete and effective.
Many GLP-1 programs offer only medication, with no additional metabolic consideration.
XMD takes a more comprehensive approach by recognizing that:
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Weight loss impacts the entire body
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Energy, metabolism, and adaptation matter
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Support beyond appetite can improve the overall experience
Offering these supports reflects a higher standard of care, not a dependency model.
Why XMD Includes This Option
What These Supports Are NOT
They are not:
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Required for success
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A replacement for nutrition
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A substitute for habits
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A shortcut to weight loss
They are tools — nothing more, nothing less.
The healthiest mindset is:
“These supports may help me feel better during my journey — but my success does not depend on them.”
This keeps expectations realistic and empowers you to focus on:
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Nutrition
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Habits
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Consistency
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Provider guidance
How to Think About Advanced Support (Best Mindset)
Final Takeaway
GLP-1 therapy stands on its own.
Advanced metabolic supports exist to:
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Enhance comfort
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Support energy
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Assist adaptation
They are a benefit when available, not a requirement.
Your journey is still complete — and effective — without them.